Welcome! Get 20% off this month for our immunoassay and flow cytometry services.
Multi-color Flow Cytometry and Cell Sorting (FACS)
Flow cytometry is a versatile and powerful technology for drug discovery and development. We offer a wide-range of flow cytometric capabilities to help our clients determine the best strategy for project needs. Our cellular and molecular analysis services are designed to accelerate immune monitoring, epitope discovery, immunophenotyping or cell isolation projects. With off-the-shelf solutions to complex flow analysis, we serve as a strategic resource with extensive capabilities to develop, validate and deploy cytometric assays for the unique examination of various parameters. Clinical development requires a wide range of flow analysis capabilities, each with its own optimization and validation. In order to support your R&D efforts, our flow cytometry services strategically align with specific drug development programs across a wide-range of therapeutic areas including cancers, autoimmune diseases and others.
Cell Sorting (FACS & MACS)
Multiplex Cytometric Bead Array (CBA)
Cell Sorting (FACS & MACS)
- FACS is routinely used in the bio-pharma industry to isolated distinct cells. Typically, cells in suspension are tagged with fluorescent antibodies, thus can be identified and isolated for further analysis or cell culture. We support protein and cell engineering and development, antibody drug development, disease identification, and characterization.
Immunophenotyping
Multiplex Cytometric Bead Array (CBA)
Cell Sorting (FACS & MACS)
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- Complexity of heterogeneous cell population analysis continues to increase as more markers are needed to differentiate functional cell subpopulations. Our powerful CytoFlex S has the capabilities to meet increased demands, such as tumor-infiltrating lymphocyte analysis.
Multiplex Cytometric Bead Array (CBA)
Multiplex Cytometric Bead Array (CBA)
Multiplex microRNA Profiling (FirePlex)
- A variety of soluble and intracellular proteins, including cytokines, chemokines, growth factors, and phosphoproteins can be measured using just 25 to 50 μL of a sample.
Multiplex microRNA Profiling (FirePlex)
Multiplex Phosphoprotein & Cell Signaling Analysis (PhosphoFlow)
Multiplex microRNA Profiling (FirePlex)
- Levels of miRNAs can be profiled directly from crude biofluids, including plasma, serum, and exosomes, without the need for RNA purification. A panel of 68 miRNAs in each sample can be measured simultaneously.
Multiplex mRNA Profiling (PrimeFlow)
Multiplex Phosphoprotein & Cell Signaling Analysis (PhosphoFlow)
Multiplex Phosphoprotein & Cell Signaling Analysis (PhosphoFlow)
- Our multiplex RNA assay reveals the dynamics of both RNA and protein expression within individual cells, facilitating unprecedented analysis of their correlation as the cell changes over time or in response to a stimulus.
Multiplex Phosphoprotein & Cell Signaling Analysis (PhosphoFlow)
Multiplex Phosphoprotein & Cell Signaling Analysis (PhosphoFlow)
Multiplex Phosphoprotein & Cell Signaling Analysis (PhosphoFlow)
- Both cell surface molecules and intracellular phosphorylated signaling proteins are simultaneously analyzed. We use well-validated phosphor-specific antibodies to quantify the signaling events in individual cells.
Cell Cycle, Proliferation, Apoptosis, and Protein Translation Analysis
Cell Cycle, Proliferation, Apoptosis, and Protein Translation Analysis
Cell Cycle, Proliferation, Apoptosis, and Protein Translation Analysis
- Combining CFSE labeling or BrdU incorporation to assess actively proliferating cells and 7-AAD to measure the proportion of live cells is an effective combination for assessing key population characteristics.
Nanoparticle Size Quantification, Cellular Uptake Analysis
Cell Cycle, Proliferation, Apoptosis, and Protein Translation Analysis
Cell Cycle, Proliferation, Apoptosis, and Protein Translation Analysis
- Our cytometer is capable of resolving 70 nm and 100 nm nanoparticles using violet laser.
- Accurate size measurements in a nanoparticle product.
- Nanoparticle uptake by cells can be monitored.
- Nanoparticle drug toxicity can be evaluated by examining relevant cellular markers such as Annexin V and cytokine production which can also be monitored simultaneously.
Custom Antibody Labeling
Cell Cycle, Proliferation, Apoptosis, and Protein Translation Analysis
Custom Antibody Labeling
- Antibodies are increasingly becoming important therapeutic agents.
- Our assays are able to label antibodies with a variety fluorescent dyes such as FITC and APC.
- Our flexible dyes options are excellent for avoiding fluorochrome compatibility issues with downstream multi-parameter techniques such as flow cytometry or fluorescence microscopy.
- Further, a fluorescent dye-conjugated test antibody facilitates more in depth studies providing mechanistic insights and potential targets.
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